- Abstract:
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OBJECTIVE: Alterations in joint mechanics can cause osteoarthritis, which results in degeneration of both cartilage and bone tissue. The objective of this work is to measure changes in the laxity of the mouse knee joint after destabilisation of the medial meniscus (DMM) and to visualise and quantify the resulting three-dimensional changes in the bone and cartilage. METHODS: Skeletally mature C57Bl6 male mice underwent DMM surgery in the right leg. Animals were sacrificed immediately 0 weeks ...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1016/j.joca.2010.11.006
-
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- Journal:
- Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society
- Volume:
- 19
- Issue:
- 2
- Pages:
- 163-170
- Publication date:
- 2011-02-05
- DOI:
- EISSN:
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1522-9653
- ISSN:
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1063-4584
- URN:
-
uuid:e0b5723f-1ce4-4067-afab-17901a78361b
- Source identifiers:
-
228438
- Local pid:
- pubs:228438
- Copyright date:
- 2011
Journal article
Multimodal imaging demonstrates concomitant changes in bone and cartilage after destabilisation of the medial meniscus and increased joint laxity.
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