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Optical recording of action potentials and other discrete physiological events: a perspective from signal detection theory.

Abstract:

Optical imaging of physiological events in real time can yield insights into biological function that would be difficult to obtain by other experimental means. However, the detection of all-or-none events, such as action potentials or vesicle fusion events, in noisy single-trial data often requires a careful balance of tradeoffs. The analysis of such experiments, as well as the design of optical reporters and instrumentation for them, is aided by an understanding of the principles of signal d...

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Publisher copy:
10.1152/physiol.00036.2006

Authors


Sjulson, L More by this author
Miesenböck, G More by this author
Journal:
Physiology (Bethesda, Md.)
Volume:
22
Issue:
1
Pages:
47-55
Publication date:
2007-02-05
DOI:
EISSN:
1548-9221
ISSN:
1548-9213
URN:
uuid:e07c7083-802f-4645-b31d-601df5be5aed
Source identifiers:
322569
Local pid:
pubs:322569

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