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The expression of ghrelin O-acyltransferase (GOAT) in human tissues

Abstract:

Ghrelin is a circulating growth hormone-releasing and appetite-inducing brain-gut peptide. It needs to be acylated on its serine-3 with octanoate for its endocrine actions. The acyl-transferase that catalyses ghrelin octanoylation has recently been identified and named as GOAT (ghrelin O-acyltransferase); GOAT enzyme is coded by the MBOAT4 gene. This study aimed to investigate GOAT expression in the human. The distribution of GOAT mRNA expression was studied in various human tissues using cla...

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Publisher copy:
10.1507/endocrj.K11E-117

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Institution:
University of Oxford
Department:
Oxford, MSD, RDM, OCDEM
Role:
Author
Journal:
Endocrine Journal
Volume:
58
Issue:
8
Pages:
707-710
Publication date:
2011-01-01
DOI:
EISSN:
1348-4540
ISSN:
0918-8959
URN:
uuid:e0624221-ff8c-41c3-9e27-3a8081e6c657
Source identifiers:
179800
Local pid:
pubs:179800

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