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Genome-wide association study identifies a common variant associated with risk of endometrial cancer.

Abstract:

Endometrial cancer is the most common malignancy of the female genital tract in developed countries. To identify genetic variants associated with endometrial cancer risk, we performed a genome-wide association study involving 1,265 individuals with endometrial cancer (cases) from Australia and the UK and 5,190 controls from the Wellcome Trust Case Control Consortium. We compared genotype frequencies in cases and controls for 519,655 SNPs. Forty seven SNPs that showed evidence of association w...

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Publication status:
Published

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Publisher copy:
10.1038/ng.812

Authors


Spurdle, AB More by this author
Thompson, DJ More by this author
Ferguson, K More by this author
Healey, CS More by this author
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Journal:
Nature genetics
Volume:
43
Issue:
5
Pages:
451-454
Publication date:
2011-05-05
DOI:
EISSN:
1546-1718
ISSN:
1061-4036
URN:
uuid:e03d2cd7-7ee3-44e1-bcd9-b8d6e4813e12
Source identifiers:
134953
Local pid:
pubs:134953

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