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Myosin V-mediated vacuole distribution and fusion in fission yeast.

Abstract:

The class V myosins are actin-based motors that move a variety of cellular cargoes [1]. In budding yeast, their activity includes the relocation of a portion of the vacuole from the mother cell to the bud [2, 3]. Fission yeast cells contain numerous (approximately 80) small vacuoles. When S. pombe cells are placed in water, vacuoles fuse in response to osmotic stress [4]. Fission yeast possess two type V myosin genes, myo51(+) and myo52(+) [5]. In a myo51Delta strain, vacuoles were distribute...

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Publication status:
Published

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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
Human Genetics Wt Centre
Role:
Author
Journal:
Current biology : CB
Volume:
11
Issue:
14
Pages:
1124-1127
Publication date:
2001-07-01
DOI:
EISSN:
1879-0445
ISSN:
0960-9822
Source identifiers:
95718
Language:
English
Keywords:
Pubs id:
pubs:95718
UUID:
uuid:e034797a-dce3-4925-a332-08349fb711ad
Local pid:
pubs:95718
Deposit date:
2012-12-19

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