Screen-detected prostate cancer and the insulin-like growth factor axis: results of a population-based case-control study.

Journal article

Higher circulating levels of IGF-I have been associated with increased risk of prostate and some other cancers. Most research on prostate cancer has been based on men with symptoms or identified following treatment of benign disease. However, increasing numbers of cancer cases are now detected in asymptomatic men following prostate-specific antigen (PSA) tests. We therefore used a population-based case-finding exercise using the PSA test to examine whether associations between the IGF axis an...

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Authors: Oliver, SE; Gunnell, D; Donovan, J; Peters, T; Persad, R

• Publication status: Published
• Journal: International journal of cancer. Journal international du cancer
• Volume: 108
• Issue: 6
• Pages: 887-892
• Publication date: 2004-03-01
• DOI: 10.1002/ijc.11631
• EISSN: 1097-0215
• ISSN: 0020-7136
• Language: English
• Keywords: Prostatic Neoplasms; Risk; Prostate-Specific Antigen; Time Factors; Odds Ratio; Aged; Mass Screening; Case-Control Studies; Tumor Markers, Biological; Middle Aged; Male; Insulin-Like Growth Factor I; Humans