Stroke prediction and stroke prevention with atorvastatin in the Collaborative Atorvastatin Diabetes Study (CARDS).

Journal article

AIMS: Patients with Type 2 diabetes have an elevated risk of stroke. The role of lipid levels and diabetes-specific factors in risk prediction of stroke is unclear, and estimates of efficacy of lipid-lowering therapy vary between trials. We examined predictors of stroke and the effect of atorvastatin on specific stroke subtypes in Type 2 diabetes in the Collaborative Atorvastatin Diabetes Study (CARDS) [a trial of 2838 participants with mean low-density lipoprotein cholesterol < 4.14 mmol...

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Authors: Hitman, G; Colhoun, H; Newman, C; Szarek, M; Betteridge, D

• Publication status: Published
• Journal: Diabetic medicine : a journal of the British Diabetic Association
• Volume: 24
• Issue: 12
• Pages: 1313-1321
• Publication date: 2007-12-01
• DOI: 10.1111/j.1464-5491.2007.02268.x
• EISSN: 1464-5491
• ISSN: 0742-3071
• Language: English
• Keywords: Female; Humans; Diabetes Mellitus, Type 2; Blood Pressure; Lipoproteins; Pyrroles; Anticholesteremic Agents; Hemoglobin A, Glycosylated; Risk Factors; Heptanoic Acids; Middle Aged; Adult; Male; CARDS Investigators; Diabetic Angiopathies; Double-Blind Method; Stroke; Aged