Journal article
Killer cell lectin-like receptor G1 inhibits NK cell function through activation of Adenosine 5'-monophosphate-activated protein kinase
- Abstract:
-
NK cells are the first line of defense against infected and transformed cells. Defective NK cell activity was shown to increase susceptibility for viral infections and reduce tumor immune-surveillance. With age, the incidence of infectious diseases and malignancy rises dramatically, suggesting that impaired NK cell function might contribute to disease in these individuals. We found an increased frequency of NK cells with high expression of the inhibitory killer cell lectin-like receptor G1 (K...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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- Publisher copy:
- 10.4049/jimmunol.1600590
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Authors
Funding
Bibliographic Details
- Publisher:
- American Association of Immunologists Publisher's website
- Journal:
- Journal of Immunology Journal website
- Volume:
- 197
- Issue:
- 7
- Pages:
- 2891-2899
- Publication date:
- 2016-10-01
- Acceptance date:
- 2016-08-01
- DOI:
- EISSN:
-
1550-6606
- ISSN:
-
0022-1767
- Pmid:
-
27566818
- Source identifiers:
-
641624
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:641624
- UUID:
-
uuid:dfde71e0-1027-4fe1-b8a0-f746df2549d3
- Local pid:
- pubs:641624
- Deposit date:
- 2016-11-02
Terms of use
- Copyright holder:
- The American Association of Immunologists, Inc
- Copyright date:
- 2016
- Notes:
- Copyright © 2016 by The American Association of Immunologists, Inc.
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