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Journal article

Host cell proteins interacting with the 3' end of TGEV coronavirus genome influence virus replication.

Abstract:

Coronavirus RNA synthesis is performed by a multienzymatic replicase complex together with cellular factors. This process requires the specific recognition of RNA cis-acting signals located at the ends of the viral genome. To identify cellular proteins involved in coronavirus RNA synthesis, transmissible gastroenteritis coronavirus (TGEV) genome ends, harboring essential cis-acting signals for replication, were used as baits for RNA affinity protein purification. Ten proteins were preferentia...

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Publication status:
Published

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Publisher copy:
10.1016/j.virol.2009.06.006

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Institution:
University of Oxford
Department:
Oxford, MSD, Pathology Dunn School
Role:
Author
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Journal:
Virology
Volume:
391
Issue:
2
Pages:
304-314
Publication date:
2009-09-05
DOI:
EISSN:
1096-0341
ISSN:
0042-6822
URN:
uuid:dfd2ce45-cf37-40ef-852e-a4c2a52c3580
Source identifiers:
58046
Local pid:
pubs:58046

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