Journal article icon

Journal article

Ibotenic acid induced demyelination in the central nervous system: a consequence of a local inflammatory response.

Abstract:

We examined the effects of injections of ibotenic acid into the medial septum (MS), dorsal lateral geniculate nucleus (dLGN), caudate-putamen (CP) or fornix-fimbria (FF) on fibres close to the injection site. Injections into the MS and dLGN resulted in demyelination. The area of demyelination correlated with the area of maximal gliosis. The major cell type in the area of gliosis were cells of haemopoietic origin, as revealed by using monoclonal antibodies (Mabs). Demyelination was not observe...

Expand abstract
Publication status:
Published

Actions

  • Cite

  • Print

Access Document

Publisher copy:
10.1016/0304-3940(88)90404-1

Authors

More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Experimental Psychology
Role:
Author
Journal:
Neuroscience letters More from this journal
Volume:
84
Issue:
2
Pages:
178-184
Publication date:
1988-01-01
DOI:
EISSN:
1872-7972
ISSN:
0304-3940
Language:
English
Keywords:
Pubs id:
pubs:5358
UUID:
uuid:dfcc79f3-0560-4bb0-bcfd-5326edf85ddc
Local pid:
pubs:5358
Source identifiers:
5358
Deposit date:
2012-12-19

Terms of use

Views and Downloads





If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP