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White matter lesions account for all age-related declines in speed but not in intelligence.

Abstract:

MRI scans measured white matter lesion prevalence (WMLP) in 65 people ages 65-84 years who also took 17 cognitive tests: 3 tests of general fluid intelligence, 3 of vocabulary, 2 of episodic and 3 of working memory, 2 of processing speed, and 4 of frontal and executive function. Entry of age with WMLP into regression equations as predictors of test scores showed that inferences about the functional relationships between markers of brain aging and cognitive impairments are seriously misleading...

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Publication status:
Published

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Publisher copy:
10.1037/0894-4105.21.3.363

Authors


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Institution:
University of Oxford
Department:
Oxford, MSD, Experimental Psychology
Thacker, N More by this author
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Journal:
Neuropsychology
Volume:
21
Issue:
3
Pages:
363-370
Publication date:
2007-05-05
DOI:
EISSN:
1931-1559
ISSN:
0894-4105
URN:
uuid:dfc5e3db-3dcb-41ae-a384-518f49bb304d
Source identifiers:
4583
Local pid:
pubs:4583

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