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Predictors of immune response and reactogenicity to AS03B-adjuvanted split virion and non-adjuvanted whole virion H1N1 (2009) pandemic influenza vaccines

Abstract:

In 2009, 943 children aged 6 months to 10 years were randomised to receive two doses of an oil-in water AS03B-adjuvanted split virion or a non-adjuvanted whole virion H1N1 (2009) vaccine. The large numbers allowed investigation of possible predictors of immune response and reactogenicity. We used regression analysis to examine the effect of variables including past receipt of seasonal vaccine, antipyretics post-vaccination, interval between doses and pre-existing antibodies to H1N1 (2009) on ...

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Authors


Andrews, NJ More by this author
Walker, WT More by this author
Collinson, AC More by this author
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Journal:
Vaccine
Volume:
29
Issue:
45
Pages:
7913-7919
Publication date:
2011-10-19
DOI:
EISSN:
1873-2518
ISSN:
0264-410X
URN:
uuid:dfbcac3e-c8d8-401e-84a8-810dc98cc117
Source identifiers:
179661
Local pid:
pubs:179661

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