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Journal article

Inducible nitric oxide synthase expression is increased in the brain in fatal cerebral malaria.

Abstract:

AIMS: Nitric oxide (NO) has been hypothesized to play a major role in the pathogenesis of cerebral malaria caused by P. falciparum infection. NO may act as a local neuroactive mediator contributing to the coma of cerebral malaria (CM). We hypothesized that increased expression of inducible nitric oxide synthase (iNOS) may cause increased release of NO, and examined the expression and distribution of iNOS in the brain during CM. MATERIAL AND RESULTS: Brain tissues from fatal cases of cerebral...

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Publication status:
Published

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Journal:
Histopathology
Volume:
37
Issue:
3
Pages:
269-277
Publication date:
2000-09-05
DOI:
EISSN:
1365-2559
ISSN:
0309-0167
URN:
uuid:dfac988f-e579-4e20-8b0f-340ca112510a
Source identifiers:
177205
Local pid:
pubs:177205

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