Journal article
Site-specific ADP-ribosylation of histone H2B in response to DNA 2 double strand breaks
- Abstract:
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ADP-ribosyltransferases (ARTs) modify proteins with single units or polymers of ADP-ribose to regulate DNA repair. However, the substrates for these enzymes are ill-defined. For example, although histones are modified by ARTs, the sites on these proteins ADP-ribosylated following DNA damage and the ARTs that catalyse these events are unknown. This, in part, is due to the lack of a eukaryotic model that contains ARTs, in addition to histone genes that can be manipulated to assess ADP-ribosylat...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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(Preview, Version of record, pdf, 1.2MB, Terms of use)
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- Publisher copy:
- 10.1038/srep43750
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Bibliographic Details
- Publisher:
- Nature Publishing Group
- Journal:
- Scientific Reports More from this journal
- Volume:
- 7
- Article number:
- 43750
- Publication date:
- 2017-01-01
- Acceptance date:
- 2017-01-26
- DOI:
- ISSN:
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2045-2322
Item Description
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- Pubs id:
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pubs:673939
- UUID:
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uuid:df9cb519-ff83-49fb-9976-07a4e48bfb4b
- Local pid:
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pubs:673939
- Source identifiers:
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673939
- Deposit date:
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2017-01-31
Terms of use
- Copyright holder:
- Rakhimova et al
- Copyright date:
- 2017
- Notes:
- This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/
- Licence:
- CC Attribution (CC BY)
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