Characterization of Bacillus species used for oral bacteriotherapy and bacterioprophylaxis of gastrointestinal disorders.

Journal article

Bacillus subtilis spores are being used for oral bacteriotherapy and bacterioprophylaxis of gastrointestinal disorders in both humans and animals. Since B. subtilis is an aerobic saprophyte, how spores may benefit the gut microbiota is an intriguing question, since other probiotics such as Lactobacillus spp. which colonize the gut are anerobes. As a first step in understanding the potential effects of ingesting spores, we have characterized five commercial products. An extensive biochemical, ...

Expand abstract

Authors: Hoa, N; Baccigalupi, L; Huxham, A; Smertenko, A; Van, P

• Journal: Applied and environmental microbiology
• Volume: 66
• Issue: 12
• Pages: 5241-5247
• Publication date: 2000-12-01
• DOI: 10.1128/aem.66.12.5241-5247.2000
• EISSN: 1098-5336
• ISSN: 0099-2240
• Language: English
• Keywords: Animals; Bacillus subtilis; Gastrointestinal Diseases; RNA, Bacterial; Humans; Probiotics; Administration, Oral; Bacillus; Species Specificity; Drug Resistance, Microbial; Base Sequence; DNA Primers; Spores, Bacterial; RNA, Ribosomal, 16S; Phylogeny; Microscopy, Electron; Genes, Bacterial