Chromosome-specific microsatellite sets for fluorescence-based, semi-automated genome mapping.

Journal article

To facilitate large-scale genetic mapping of the human genome, we have developed chromosome-specific sets of microsatellite marker loci suitable for use with a fluorescence-based automated DNA fragment analyser. We present 254 dinucleotide repeat marker loci (80% from the Généthon genetic linkage map) arranged into 39 sets, covering all 22 autosomes and the X chromosome. The average distance between adjacent markers is 13 centiMorgans, and less than 4% of the genome lies more than 20 cM from ...

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Authors: Reed, P; Davies, J; Copeman, J; Bennett, S; Palmer, S

• Journal: Nature genetics
• Volume: 7
• Issue: 3
• Pages: 390-395
• Publication date: 1994-07-01
• DOI: 10.1038/ng0794-390
• EISSN: 1546-1718
• ISSN: 1061-4036
• Language: English
• Keywords: Base Sequence; Repetitive Sequences, Nucleic Acid; Chromosomes, Human; Genetic Markers; DNA, Satellite; Automation; Fluorescent Dyes; DNA Probes; Genome, Human; Software; Molecular Sequence Data; Polymorphism, Genetic; Chromosome Mapping; Humans; Male; Female