- Abstract:
-
Negatively charged poly(lactic-co-glycolic acid) (PLGA) microspheres encapsulated with hydrophilic drugs have been successfully prepared by a solidin-oil-in-water (s/o/w) solvent evaporation method in the presence of anionic surfactants, sodium dodecyl sulfate (SDS), and dioctyl sodium sulfosuccinate (DSS), and nonionic surfactant polyvinyl alcohol (PVA). The effects of microencapsulation methods, surfactants types, and surfactant concentrations on the properties of microspheres were studied....
Expand abstract - Publisher copy:
- 10.1002/jps.21612
-
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- Journal:
- Journal of Pharmaceutical Sciences
- Volume:
- 98
- Issue:
- 7
- Pages:
- 2377-2389
- Publication date:
- 2009-07-05
- DOI:
- EISSN:
-
1520-6017
- ISSN:
-
0022-3549
- URN:
-
uuid:df8cfd71-9a00-4548-abf7-52d095964178
- Source identifiers:
-
178850
- Local pid:
- pubs:178850
- Language:
- English
- Keywords:
- Copyright date:
- 2009
Journal article
Preparation and characterization of negatively charged poly(lactic-co- glycolic acid) microspheres
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