Travelling-wave ion mobility mass spectrometry and negative ion fragmentation of hybrid and complex N-glycans.
Nitrogen CCSs (CCSs) of hybrid and complex glycans released from the glycoproteins IgG, gp120 (from human immunodeficiency virus), ovalbumin, α1-acid glycoprotein and thyroglobulin were measured with a travelling-wave ion mobility mass spectrometer using dextran as the calibrant. The utility of this instrument for isomer separation was also investigated. Some isomers, such as Man3 GlcNAc3 from chicken ovalbumin and Man3 GlcNAc3 Fuc1 from thyroglobulin could be partially resolved and identifie...Expand abstract
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- Peer reviewed
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- Copyright © 2016 John Wiley & Sons, Ltd
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- Copyright © 2016 John Wiley & Sons, Ltd. Published by Wiley.
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