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Journal article

Travelling-wave ion mobility mass spectrometry and negative ion fragmentation of hybrid and complex N-glycans.

Abstract:

Nitrogen CCSs (CCSs) of hybrid and complex glycans released from the glycoproteins IgG, gp120 (from human immunodeficiency virus), ovalbumin, α1-acid glycoprotein and thyroglobulin were measured with a travelling-wave ion mobility mass spectrometer using dextran as the calibrant. The utility of this instrument for isomer separation was also investigated. Some isomers, such as Man3 GlcNAc3 from chicken ovalbumin and Man3 GlcNAc3 Fuc1 from thyroglobulin could be partially resolved and identifie...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1002/jms.3828

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Institution:
University of Oxford
Division:
MSD
Department:
Biochemistry
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Biochemistry
Role:
Author
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Publisher:
Wiley Publisher's website
Journal:
Journal of Mass Spectrometry Journal website
Publication date:
2016-07-31
Acceptance date:
2016-07-31
DOI:
EISSN:
1096-9888
Source identifiers:
637299
Language:
English
Keywords:
Pubs id:
pubs:637299
UUID:
uuid:df4f0c09-60ca-4d91-90d2-d2be12767d01
Local pid:
pubs:637299
Deposit date:
2016-08-16

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