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The structure of a cypovirus and the functional organization of dsRNA viruses.

Abstract:

Cytoplasmic polyhedrosis virus (CPV) is unique among the double-stranded RNA viruses of the family Reoviridae in having a single capsid layer. Analysis by cryo-electron microscopy allows comparison of the single shelled CPV and orthoreovirus with the high resolution crystal structure of the inner shell of the bluetongue virus (BTV) core. This suggests that the novel arrangement identified in BTV, of 120 protein subunits in a so-called 'T=2' organization, is a characteristic of the Reoviridae ...

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Publication status:
Published

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Publisher copy:
10.1038/9347

Authors


Prasad, BV More by this author
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Institution:
University of Oxford
Department:
Oxford, MSD, NDM, Structural Biology
Mertens, PP More by this author
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Journal:
Nature structural biology
Volume:
6
Issue:
6
Pages:
565-568
Publication date:
1999-06-05
DOI:
ISSN:
1072-8368
URN:
uuid:df4e58c3-339a-466f-9dcf-da604d2677e0
Source identifiers:
11800
Local pid:
pubs:11800

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