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Thesis

Within-host evolution of HIV-1 and the analysis of transmissible diversity

Abstract:

The central problem for researchers of HIV-1 evolution is explaining the apparent design of the virus for causing pandemic infection in humans: understanding how HIV-1 spreads is key to halting the pandemic. Current knowledge of how HIV-1 spreads from host to host is based upon experimental observation and indirect inferences informed by theory. The hypothesis of this thesis is that diversity of HIV-1 around the time of transmission is important for viral adaptation to a new human host, ra...

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Role:
Supervisor
Role:
Supervisor
Institution:
University of Oxford
Department:
Medical Sciences Division - Clinical Medicine,Nuffield Department of
Publication date:
2012
Type of award:
DPhil
Level of award:
Doctoral
URN:
uuid:df24b49c-fb27-49a3-bd2e-3e38008e9da4
Local pid:
ora:12148

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