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A randomised controlled trial of extended anticoagulation treatment versus standard treatment for the prevention of recurrent venous thromboembolism (VTE) and post-thrombotic syndrome in patients being treated for a first episode of unprovoked VTE (the ExACT study)

Abstract:

Venous thromboembolism (VTE) is prevalent and impactful, with a risk of death, morbidity and recurrence. Post‐thrombotic syndrome (PTS) is a common consequence and associated with impaired quality of life (QoL). The ExACT study was a non‐blinded, prospective, multicentred randomised controlled trial comparing extended versus limited duration anticoagulation following a first unprovoked VTE (proximal deep vein thrombosis or pulmonary embolism). Adults were eligible if they had completed ≥3 mon...

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Publication status:
Published
Peer review status:
Peer reviewed

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Files:
Publisher copy:
10.1111/bjh.16275

Authors


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Role:
Author
ORCID:
0000-0001-5248-8165
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Institution:
University of Oxford
Division:
MSD
Department:
Primary Care Health Sciences
Oxford college:
Kellogg College
Role:
Author
Publisher:
Wiley
Journal:
British Journal of Haematology More from this journal
Volume:
188
Issue:
6
Pages:
962-975
Publication date:
2019-11-12
Acceptance date:
2019-10-06
DOI:
EISSN:
1365-2141
ISSN:
0007-1048
Pmid:
31713863
Language:
English
Keywords:
Pubs id:
pubs:1072536
UUID:
uuid:defb2584-56e8-4c23-aeef-09929532078b
Local pid:
pubs:1072536
Source identifiers:
1072536
Deposit date:
2020-01-07

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