- Abstract:
-
OBJECTIVE: To examine peripheral leukocyte Dectin-1 regulation in clinically relevant models of fungal and polymicrobial sepsis. DESIGN: Prospective animal study. SETTING: University medical school research laboratory. SUBJECTS: Age, weight, and sex matched ICR/HSD mice. INTERVENTIONS: Mice were infected with Candida albicans (1 x 10, intravenously) or were subjected to cecal ligation and puncture to induce polymicrobial sepsis. MEASUREMENTS: Blood, spleen, and peritoneal exudate were harvest...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1097/ccm.0b013e3181968fa0
-
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- Journal:
- Critical care medicine
- Volume:
- 37
- Issue:
- 3
- Pages:
- 1038-1045
- Publication date:
- 2009-03-05
- DOI:
- EISSN:
-
1530-0293
- ISSN:
-
0090-3493
- URN:
-
uuid:ded739f0-7433-4a4f-b4f5-2e95e62e9dc9
- Source identifiers:
-
18878
- Local pid:
- pubs:18878
- Language:
- English
- Keywords:
- Copyright date:
- 2009
Journal article
Leukocyte Dectin-1 expression is differentially regulated in fungal versus polymicrobial sepsis.
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