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The UK experience in treating relapsed childhood acute lymphoblastic leukaemia: a report on the medical research council UKALLR1 study.

Abstract:

We have examined the toxicity and overall outcome of the Medical Research Council UKALL R1 protocol for 256 patients with relapsed childhood acute lymphoblastic leukaemia (ALL). Second remission was achieved in over 95% of patients. Two patients died during induction and seven patients died of resistant disease. The overall actuarial event-free survival (EFS) at 5 years for all patients experiencing a first relapse was 46% (95% CI 40-52). Duration of first remission, site of relapse, age at d...

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Publication status:
Published

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Authors


Lawson, SE More by this author
Harrison, G More by this author
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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Trial Service Unit
Oakhill, A More by this author
Stevens, R More by this author
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Journal:
British journal of haematology
Volume:
108
Issue:
3
Pages:
531-543
Publication date:
2000-03-05
DOI:
EISSN:
1365-2141
ISSN:
0007-1048
URN:
uuid:de62b73f-452e-40ef-8799-f205b5bdd367
Source identifiers:
66583
Local pid:
pubs:66583

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