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Journal article

Traveling-wave ion mobility mass spectrometry of protein complexes: accurate calibrated collision cross-sections of human insulin oligomers.

Abstract:

RATIONALE: The collision cross-section (Ω) of a protein or protein complex ion can be measured using traveling-wave (T-wave) ion mobility (IM) mass spectrometry (MS) via calibration with compounds of known Ω. The T-wave Ω-values depend strongly on instrument parameters and calibrant selection. Optimization of instrument parameters and calibration standards are crucial for obtaining accurate T-wave Ω-values. METHODS: Human insulin and the fast-acting insulin aspart under native-like condition...

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Publication status:
Published

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Publisher copy:
10.1002/rcm.6211

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Journal:
Rapid communications in mass spectrometry : RCM
Volume:
26
Issue:
10
Pages:
1181-1193
Publication date:
2012-05-05
DOI:
EISSN:
1097-0231
ISSN:
0951-4198
URN:
uuid:de4f7e44-7fae-4d01-97f2-c1adde43b5c2
Source identifiers:
325391
Local pid:
pubs:325391

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