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A novel approach to ultrasound-mediated tissue decellularization and intra-hepatic cell delivery in rats

Abstract:

Liver transplantation is the mainstay of treatment for end stage liver diseases, including metabolic and congenital liver diseases. The number of suitable donor organs is, however, limited, and a whole-liver transplant requires complex surgery. Cell therapy, such as intra-portal hepatocytes transplantation, has been considered as a bridging therapy to liver transplantation but has shown a mixed clinical outcome with limited success, including low level of engraftment of transplanted hepatocyt...

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Publication status:
Published
Peer review status:
Peer reviewed

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Institution:
University of Oxford
Division:
MSD
Department:
Physiology Anatomy & Genetics
Role:
Author
Publisher:
Elsevier
Journal:
Ultrasound in Medicine and Biology More from this journal
Volume:
42
Issue:
8
Pages:
1958-1967
Publication date:
2016-05-13
Acceptance date:
2016-03-20
DOI:
EISSN:
1879-291X
ISSN:
0301-5629
Language:
English
Keywords:
Pubs id:
pubs:710198
UUID:
uuid:de0bc726-9bf7-4211-9409-6bbada5d4ea5
Local pid:
pubs:710198
Source identifiers:
710198
Deposit date:
2017-10-12

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