- Abstract:
-
Phage display technology was used to identify peptide ligands with unique specificity for a monoclonal model antibody, MK16, that recognises the human multiple sclerosis associated MHC class II molecule DR2 in complex with a myelin basic protein (MBP)-derived peptide corresponding to residue 85-99. Several peptide epitopes were identified and all of them recognised specifically MK16. One peptide, ER6.1, was selected and linked to beaded agarose and demonstrated excellent performance as a pept...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1016/j.jim.2003.10.001
-
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- Journal:
- Journal of immunological methods
- Volume:
- 284
- Issue:
- 1-2
- Pages:
- 45-54
- Publication date:
- 2004-01-05
- DOI:
- EISSN:
-
1872-7905
- ISSN:
-
0022-1759
- URN:
-
uuid:de0abc2f-04c8-4420-863c-e89685e77b2b
- Source identifiers:
-
314760
- Local pid:
- pubs:314760
- Copyright date:
- 2004
Journal article
Efficient purification of unique antibodies using peptide affinity-matrix columns.
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