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Journal article

Efficient purification of unique antibodies using peptide affinity-matrix columns.

Abstract:

Phage display technology was used to identify peptide ligands with unique specificity for a monoclonal model antibody, MK16, that recognises the human multiple sclerosis associated MHC class II molecule DR2 in complex with a myelin basic protein (MBP)-derived peptide corresponding to residue 85-99. Several peptide epitopes were identified and all of them recognised specifically MK16. One peptide, ER6.1, was selected and linked to beaded agarose and demonstrated excellent performance as a pept...

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Publication status:
Published

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Publisher copy:
10.1016/j.jim.2003.10.001

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Journal:
Journal of immunological methods
Volume:
284
Issue:
1-2
Pages:
45-54
Publication date:
2004-01-05
DOI:
EISSN:
1872-7905
ISSN:
0022-1759
URN:
uuid:de0abc2f-04c8-4420-863c-e89685e77b2b
Source identifiers:
314760
Local pid:
pubs:314760

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