Journal article icon

Journal article

Myosin II regulates complex cellular arrangement and epithelial architecture in Drosophila.

Abstract:

Remodeling epithelia is a primary driver of morphogenesis. Here, we report a central role of myosin II in regulating several aspects of complex epithelial architecture in the Drosophila eye imaginal disc. The epithelial indentation of the morphogenetic furrow is established from a pattern of myosin II activation defined by the developmental signals Hedgehog and Decapentaplegic. More generally, patterned myosin activation can control diverse three-dimensional epithelial sculpting. We have deve...

Expand abstract
Publication status:
Published

Actions


Access Document


Authors


Escudero, LM More by this author
Bischoff, M More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Pathology Dunn School
Journal:
Developmental cell
Volume:
13
Issue:
5
Pages:
717-729
Publication date:
2007-11-05
DOI:
EISSN:
1878-1551
ISSN:
1534-5807
URN:
uuid:ddfc6864-f13a-4bbe-8c66-b0901dcaa429
Source identifiers:
356055
Local pid:
pubs:356055

Terms of use


Metrics



If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP