- Abstract:
-
Remodeling epithelia is a primary driver of morphogenesis. Here, we report a central role of myosin II in regulating several aspects of complex epithelial architecture in the Drosophila eye imaginal disc. The epithelial indentation of the morphogenetic furrow is established from a pattern of myosin II activation defined by the developmental signals Hedgehog and Decapentaplegic. More generally, patterned myosin activation can control diverse three-dimensional epithelial sculpting. We have deve...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1016/j.devcel.2007.09.002
-
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- Journal:
- Developmental cell
- Volume:
- 13
- Issue:
- 5
- Pages:
- 717-729
- Publication date:
- 2007-11-05
- DOI:
- EISSN:
-
1878-1551
- ISSN:
-
1534-5807
- URN:
-
uuid:ddfc6864-f13a-4bbe-8c66-b0901dcaa429
- Source identifiers:
-
356055
- Local pid:
- pubs:356055
- Language:
- English
- Keywords:
- Copyright date:
- 2007
Journal article
Myosin II regulates complex cellular arrangement and epithelial architecture in Drosophila.
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