Journal article icon

Journal article

Clinical genomics in inflammatory bowel disease

Abstract:

Genomic technologies inform the complex genetic basis of polygenic inflammatory bowel disease (IBD) as well as Mendelian disease-associated IBD. Aiming to diagnose patients that present with extreme phenotypes due to monogenic forms of IBD, genomics has progressed from 'orphan disease' research towards an integrated standard of clinical care. Advances in diagnostic clinical genomics are increasingly complemented by pathway-specific therapies that aim to correct the consequences of genetic def...

Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

Actions


Access Document


Files:
Publisher copy:
10.1016/j.tig.2017.06.008

Authors


More by this author
Department:
Oxford, MSD, NDM, NDM Experimental Medicine
Role:
Author
Expand funders...
Publisher:
Elsevier Publisher's website
Journal:
Trends in genetics Journal website
Volume:
33
Issue:
9
Pages:
629-641
Publication date:
2017-07-26
Acceptance date:
2017-06-27
DOI:
ISSN:
0168-9525 and 1362-4555
Pubs id:
pubs:710247
URN:
uri:ddf4097b-583e-454e-bac2-a28d318337db
UUID:
uuid:ddf4097b-583e-454e-bac2-a28d318337db
Local pid:
pubs:710247

Terms of use


Metrics


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP