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Journal article

A randomised trial of near infra-red spectroscopy for the personalised optimisation of cerebral tissue oxygenation during cardiac surgery

Abstract:

Background

We assessed whether a Near Infra-Red Spectroscopy (NIRS) based algorithm for the personalised optimisation of cerebral oxygenation during cardiopulmonary bypass (CPB) combined with a restrictive red cell transfusion threshold would reduce perioperative injury to the brain, heart and kidneys.

Methods

In a randomised controlled trial participants in 3 UK centres were randomised with concealed allocation to a NIRS (INVOS 5100, Medtronic Inc, MN, USA) based...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Accepted manuscript

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Publisher copy:
10.1093/bja/aex182

Authors


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Department:
Oxford, MSD, Nuffield Dept of Population Health, Population Health
Role:
Author
More by this author
Department:
Oxford, MSD, Nuffield Dept of Population Health, Population Health
Role:
Author
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Publisher:
Oxford University Press Publisher's website
Journal:
British Journal of Anaesthesia Journal website
Volume:
119
Issue:
3
Pages:
384–393
Publication date:
2017-07-19
Acceptance date:
2017-04-20
DOI:
EISSN:
1471-6771
ISSN:
0007-0912
Pubs id:
pubs:703056
URN:
uri:dde73a84-8928-4073-8b49-abbbbc3f2354
UUID:
uuid:dde73a84-8928-4073-8b49-abbbbc3f2354
Local pid:
pubs:703056

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