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Journal article

Anecdotes that provide definitive evidence

Abstract:

Many adverse drug reactions are first reported anecdotally. Anecdotal reports, by which we mean either individual cases or small case series, are generally regarded as providing poor quality evidence. They therefore usually require formal verification through robust epidemiological studies or clinical trials, although a minority are actually verified. However, we propose that some adverse drug reactions are so convincing, even without traditional chronological causal criteria such as challeng...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1136/bmj.39036.666389.94

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Institution:
University of Oxford
Department:
Medical Sciences Division - Clinical Pharmacology
Role:
Author
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Institution:
"Risk Management Strategy, Pfizer, New York, USA"
Role:
Author
Journal:
BMJ Journal website
Volume:
333
Issue:
7581
Pages:
1267-1269.
Publication date:
2006-12-05
DOI:
EISSN:
1468-5833
ISSN:
0959-8154
URN:
uuid:dde0582a-6622-4dfa-a437-1acd4287f83d
Local pid:
ora:1022
Language:
English
Keywords:
Subjects:

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