- Abstract:
-
Cell-cycle progression is governed by a series of essential regulatory proteins. Two major regulators are cell-division cycle protein 20 (CDC20) and its homologue, CDC20 homologue 1 (CDH1), which activate the anaphase-promoting complex/cyclosome (APC/C) in mitosis, and facilitate degradation of mitotic APC/C substrates. The malaria parasite, Plasmodium, is a haploid organism which, during its life-cycle undergoes two stages of mitosis; one associated with asexual multiplication and the other ...
Expand abstract - Publication status:
- Published
- Peer review status:
- Peer reviewed
- Version:
- Publisher's Version
- Files:
-
-
(pdf, 3.6mb)
-
- Publisher copy:
- 10.1371/journal.ppat.1002554
-
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- Publisher:
- Public Library of Science Publisher's website
- Journal:
- PLoS Pathogens Journal website
- Volume:
- 8
- Issue:
- 2
- Pages:
- e1002554
- Publication date:
- 2012-02-23
- Acceptance date:
- 2012-01-12
- DOI:
- EISSN:
-
1553-7374
- ISSN:
-
1553-7366
- URN:
-
uuid:ddd7805d-6346-4493-b80d-5e6b71ae6873
- Source identifiers:
-
334152
- Local pid:
- pubs:334152
- Language:
- English
- Keywords:
- Copyright holder:
- Guttery et al.
- Copyright date:
- 2012
- Notes:
- © 2012 Guttery et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Journal article
A putative homologue of CDC20/CDH1 in the malaria parasite is essential for male gamete development
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