Journal article icon

Journal article

Therapeutic potential of folate uptake inhibition in Plasmodium falciparum.

Abstract:
Plasmodium falciparum parasites resistant to the combination sulfadoxine-pyrimethamine are spreading in Africa, particularly in East Africa. This is a matter of concern because there are no other affordable drugs available. This article provides the evidence indicating that sulfadoxine-pyrimethamine resistance can be reversed in vitro and discusses how this information might be exploited to extend the therapeutic lifetime of sulfadoxine-pyrimethamine in vivo.
Publication status:
Published

Actions


Access Document


Publisher copy:
10.1016/j.pt.2003.12.005

Authors


More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, Tropical Medicine
Role:
Author
Journal:
Trends in parasitology
Volume:
20
Issue:
3
Pages:
109-112
Publication date:
2004-03-05
DOI:
EISSN:
1471-5007
ISSN:
1471-4922
URN:
uuid:ddb9dc16-24da-461e-aa06-6e454c309d5b
Source identifiers:
33465
Local pid:
pubs:33465

Terms of use


Metrics


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP