Characterizing single-molecule FRET dynamics with probability distribution analysis.
Probability distribution analysis (PDA) is a recently developed statistical tool for predicting the shapes of single-molecule fluorescence resonance energy transfer (smFRET) histograms, which allows the identification of single or multiple static molecular species within a single histogram. We used a generalized PDA method to predict the shapes of FRET histograms for molecules interconverting dynamically between multiple states. This method is tested on a series of model systems, including bo...Expand abstract
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- Chemphyschem : a European journal of chemical physics and physical chemistry
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