Journal article
A randomized, double-blind placebo controlled trial of balapiravir, a polymerase inhibitor, in adult dengue patients
- Abstract:
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Background: Dengue is the most common arboviral infection of humans. There are currently no specific treatments for dengue. Balapiravir is a prodrug of a nucleoside analogue (called R1479) and an inhibitor of hepatitis C virus replication in vivo.
Expand abstract
Methods: We conducted in vitro experiments to determine the potency of balapiravir against dengue viruses and then an exploratory, dose-escalating, randomized placebo-controlled trial in adult male...
- Publication status:
- Published
- Peer review status:
- Peer reviewed
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(Preview, Version of record, pdf, 1.2MB, Terms of use)
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- Publisher copy:
- 10.1093/infdis/jis470
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Bibliographic Details
- Publisher:
- Oxford University Press
- Journal:
- Journal of Infectious Diseases More from this journal
- Volume:
- 207
- Issue:
- 9
- Pages:
- 1442–1450
- Publication date:
- 2012-07-17
- Acceptance date:
- 2012-03-14
- DOI:
- EISSN:
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1537-6613
- ISSN:
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0022-1899
- Pmid:
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22807519
Item Description
- Keywords:
- Pubs id:
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pubs:342305
- UUID:
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uuid:dd45cf9c-f358-4698-b2e1-55cb33c414ea
- Local pid:
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pubs:342305
- Source identifiers:
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342305
- Deposit date:
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2017-04-26
Terms of use
- Copyright holder:
- Nguyet et al
- Copyright date:
- 2012
- Notes:
- © The Authors 2012. Published by Oxford University Press on behalf of the Infectious Diseases Society of America. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
- Licence:
- CC Attribution (CC BY)
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