- Abstract:
-
Cep135/Bld10 is a conserved centriolar protein required for the formation of the central cartwheel, an early intermediate in centriole assembly. Surprisingly, Cep135/Bld10 is not essential for centriole duplication in Drosophila, suggesting either that Cep135/Bld10 is not essential for cartwheel formation, or that the cartwheel is not essential for centriole assembly in flies. Using electron tomography and super-resolution microscopy we show that centrioles can form a cartwheel in the absence...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1242/jcs.113506
-
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- Journal:
- Journal of cell science
- Volume:
- 125
- Issue:
- Pt 23
- Pages:
- 5881-5886
- Publication date:
- 2012-12-05
- DOI:
- EISSN:
-
1477-9137
- ISSN:
-
0021-9533
- URN:
-
uuid:dd24b4a2-4af9-4e6b-ae79-132d76a15a0e
- Source identifiers:
-
352443
- Local pid:
- pubs:352443
- Language:
- English
- Keywords:
- Copyright date:
- 2012
Journal article
Drosophila Cep135/Bld10 maintains proper centriole structure but is dispensable for cartwheel formation.
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