Conference item icon

Conference item

Polymorphisms in the p53 pathway are enriched in cancer susceptibility loci and share characteristics with somatic pathway mutations

Abstract:
Commonly inherited genetic variants, such as single nucleotide polymorphisms (SNPs) hold great promise as easily obtainable and measurable biomarkers. Over one thousand SNPs associate with cancer in genome-wide association studies (GWAS). However, the limited understanding of the biology behind these associations has restricted their utility.
Publication status:
Published
Peer review status:
Reviewed (Other)
Version:
Accepted manuscript

Actions


Access Document


Files:
Publisher copy:
10.1016/S0959-8049(16)61634-9

Authors


Stracquadanio, G More by this author
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Oncology
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
NDM; Ludwig Institute
Expand authors...
Ludwig Institute for Cancer Research More from this funder
Publisher:
Elsevier Publisher's website
Publication date:
2016-07-01
DOI:
EISSN:
1879-0852
ISSN:
0959-8049
Pubs id:
pubs:855806
URN:
uri:dd201da5-47bf-46cb-bbb6-43d4e4186bc2
UUID:
uuid:dd201da5-47bf-46cb-bbb6-43d4e4186bc2
Local pid:
pubs:855806

Terms of use


Metrics



If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP