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Journal article

Inflammation-induced lymphangiogenesis in the cornea arises from CD11b-positive macrophages.

Abstract:

In the inflamed cornea, there is a parallel outgrowth of blood and lymphatic vessels into the normally avascular cornea. We tested whether adaptive and/or innate immune cells were actively involved in the genesis of new lymphatic vessels. Our results indicate that innate immune cells (CD11b+ macrophages, but not CD11c+ dendritic cells) physically contributed to lymphangiogenesis under pathological conditions and that bone marrow-derived CD11b+ macrophages expressed lymphatic endothelial marke...

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Publication status:
Published

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Publisher copy:
10.1172/jci23874

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Journal:
The Journal of clinical investigation
Volume:
115
Issue:
9
Pages:
2363-2372
Publication date:
2005-09-05
DOI:
EISSN:
1558-8238
ISSN:
0021-9738
URN:
uuid:dd1bc70a-2509-4f43-afd8-232a8a1569e9
Source identifiers:
102509
Local pid:
pubs:102509

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