- Abstract:
- Site-selective glycosylation by Se-S-mediated ligation has led to the efficient formation of a wide variety of conjugates 1 without the need for a large excess of the carbohydrate reagent. By this convergent method it was possible to introduce a heptasaccharide glycan selectively, and to perform a multiple site-selective chemical glycosylation of protein. A chemically Cysglycosylated glycoprotein was elaborated enzymatically.
- Publication status:
- Published
- Publisher copy:
- 10.1002/anie.200352975
-
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- Journal:
- Angewandte Chemie (International ed. in English)
- Volume:
- 43
- Issue:
- 7
- Pages:
- 828-833
- Publication date:
- 2004-02-05
- DOI:
- EISSN:
-
1521-3773
- ISSN:
-
1433-7851
- URN:
-
uuid:dd180df0-4765-41b1-bd19-1074077c2547
- Source identifiers:
-
32620
- Local pid:
- pubs:32620
- Copyright date:
- 2004
Journal article
Glyco-SeS: selenenylsulfide-mediated protein glycoconjugation--a new strategy in post-translational modification.
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