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Warfarin versus aspirin for stroke prevention in an elderly community population with atrial fibrillation (the Birmingham Atrial Fibrillation Treatment of the Aged Study, BAFTA): a randomised controlled trial.

Abstract:

BACKGROUND: Anticoagulants are more effective than antiplatelet agents at reducing stroke risk in patients with atrial fibrillation, but whether this benefit outweighs the increased risk of bleeding in elderly patients is unknown. We assessed whether warfarin reduced risk of major stroke, arterial embolism, or other intracranial haemorrhage compared with aspirin in elderly patients. METHODS: 973 patients aged 75 years or over (mean age 81.5 years, SD 4.2) with atrial fibrillation were recruit...

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Publication status:
Published

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Authors


Fletcher, K More by this author
Fitzmaurice, D More by this author
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Journal:
Lancet
Volume:
370
Issue:
9586
Pages:
493-503
Publication date:
2007-08-05
DOI:
EISSN:
1474-547X
ISSN:
0140-6736
URN:
uuid:dcec06ef-9a3d-4e27-8246-8dcc50c4ba56
Source identifiers:
122528
Local pid:
pubs:122528

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