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Journal article

Potency assays for novel T-cell-inducing vaccines against malaria.

Abstract:

The complex life cycle of the malaria parasite involves several developmental stages in the mammalian host that provide opportunities for vaccine intervention. The effector arm of the immune response that protects against malaria is specific for each stage of the parasite life cycle. While CD4+ and CD8+ T-cells are required to mediate protection during the liver stage, antibodies play a major role before parasite entry into the liver and during the blood stage. Induction of cytotoxic T-cells ...

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Publication status:
Published

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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine
Role:
Author
Journal:
Current opinion in molecular therapeutics
Volume:
11
Issue:
1
Pages:
72-80
Publication date:
2009-02-05
EISSN:
2040-3445
ISSN:
1464-8431
URN:
uuid:dce748ff-0a17-491f-9cb0-d64ab849d95b
Source identifiers:
266816
Local pid:
pubs:266816
Language:
English
Keywords:

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