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Liver fat measured by mr spectroscopy: Estimate of imprecision and relationship with serum glycerol, caeruloplasmin and non-esterified fatty acids

Abstract:

Magnetic resonance spectroscopy (MRS) is a non-invasive method for quantitative estimation of liver fat. Knowledge of its imprecision, which comprises biological variability and measurement error, is required to design therapeutic trials with measurement of change. The role of adipocyte lipolysis in ectopic fat accumulation remains unclear. We examined the relationship between liver fat content and indices of lipolysis, and determine whether lipolysis reflects insulin resistance or metabolic ...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.3390/ijms17071089

Authors


Williams, S More by this author
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ORCID:
0000-0003-2185-4999
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Wellcome Trust More from this funder
National Institute of Health Research More from this funder
Publisher:
MDPI Publisher's website
Journal:
International Journal of Molecular Sciences Journal website
Volume:
17
Issue:
7
Pages:
Article: 1089
Publication date:
2016-07-08
Acceptance date:
2016-06-30
DOI:
EISSN:
1422-0067
ISSN:
1422-0067
Pubs id:
pubs:636316
URN:
uri:dce159ad-5120-4d3e-98d4-8f2c52308ea1
UUID:
uuid:dce159ad-5120-4d3e-98d4-8f2c52308ea1
Local pid:
pubs:636316

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