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Influenza virus-specific cytotoxic T cells in man; induction and properties of the cytotoxic cell.

Abstract:

Human peripheral blood lymphocytes have been sensitized in vitro to influenza virus antigen. After an induction period of 4--14 days, cytotoxic cells which lyse autologous influenza virus-infected lymphoid cells could be demonstrated. The cytotoxic cell is a T lymphocyte which shows specificity for sensitizing influenza virus type A or B. It cannot distinguish between major subtypes of influenza A virus. The use of virus-infected normal lymphoid cells as target cells overcame the difficulties...

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Publication status:
Published

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Publisher copy:
10.1002/eji.1830081007

Authors


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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, Experimental Medicine Division,
Askonas, BA More by this author
Journal:
European journal of immunology
Volume:
8
Issue:
10
Pages:
705-711
Publication date:
1978-10-05
DOI:
EISSN:
1521-4141
ISSN:
0014-2980
URN:
uuid:dcde7a79-e03c-4940-93ec-b69b7b8a5672
Source identifiers:
41698
Local pid:
pubs:41698

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