Stroke in the developing brain and intractable epilepsy: effect of timing on hippocampal sclerosis.

Journal article

A detailed study was made of the pathology of specimens removed by hemispherectomy for the treatment of intractable epilepsy in children with unilateral middle cerebral artery stroke. Neuropathological criteria were used to differentiate strokes that occurred in early intrauterine development (before 28 weeks gestational age) from those occurring in the last trimester, at birth, or after birth: 19 children had early strokes and 21 late. There was no difference in seizure history or occurrence...

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Authors: Squier, W; Salisbury, H; Sisodiya, S

• Publication status: Published
• Journal: Developmental medicine and child neurology
• Volume: 45
• Issue: 9
• Pages: 580-585
• Publication date: 2003-09-01
• DOI: 10.1017/s0012162203001075
• EISSN: 1469-8749
• ISSN: 0012-1622
• Language: English
• Keywords: Time Factors; Humans; Adolescent; Epilepsy; Child, Preschool; Stroke; Canada; Sclerosis; Infant; Infant, Newborn; Child; Hippocampus; Brain; Great Britain; Male; Immunohistochemistry; Female; Child Welfare