Journal article icon

Journal article

Mediation mechanism of tyrosine 185 on the retinal isomerization equilibrium and the proton release channel in the seven-transmembrane receptor bacteriorhodopsin.

Abstract:

Electrostatic coupling leading to conformational changes in proteins is challenging to demonstrate directly, it requires that both the local, discrete electronic details and dynamic information relevant to the functional descriptions are probed. Here, as a novel study to address this challenge, the roles of an aromatic residue in influencing the functional conformational changes of a membrane receptor in its natural membrane environment are reported. Previously intractable discrete electronic...

Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed
Version:
Accepted Manuscript

Actions


Access Document


Files:
Publisher copy:
10.1016/j.bbabio.2016.08.002

Authors


Expand authors...
Expand funders...
Publisher:
Elsevier Publisher's website
Journal:
Biochimica et Biophysica Acta (BBA) - Bioenergetics Journal website
Volume:
1857
Issue:
11
Pages:
1786-1795
Publication date:
2016-08-09
Acceptance date:
2016-08-06
DOI:
ISSN:
0006-3002
Pubs id:
pubs:638854
URN:
uri:dcb502d5-0ccb-41d8-95c9-81ec9a42661c
UUID:
dcb502d5-0ccb-41d8-95c9-81ec9a42661c
Local pid:
pubs:638854

Terms of use


Metrics


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP