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Journal article

L-Arginine, the substrate for NO synthesis: an alternative treatment for premature atherosclerosis?

Abstract:

L-Arginine is the substrate of endothelial nitric oxide synthase (eNOS) and the main precursor of nitric oxide (NO) in the vascular endothelium. L-Arginine improves endothelial function in patients with hypercholesterolemia, hypertension and smokers, while its role in diabetes remains unclear. Oral supplementation of L-arginine leads to a significant improvement of endothelium-dependent forearm vasodilation in hypercholesterolemic patients, while intravenous infusion of L-arginine improves en...

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Journal:
International journal of cardiology
Volume:
116
Issue:
3
Pages:
300-308
Publication date:
2007-04-05
DOI:
EISSN:
1874-1754
ISSN:
0167-5273
URN:
uuid:dca14c42-2e61-4261-8992-db3c28698f44
Source identifiers:
223229
Local pid:
pubs:223229

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