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T-cell responses are associated with survival in acute Melioidosis patients

Abstract:
Background: Melioidosis is an increasingly recognised cause of sepsis and death across South East Asia and Northern Australia, caused by the bacterium Burkholderia pseudomallei. Risk factors include diabetes, alcoholism and renal disease, and a vaccine targeting at-risk populations is urgently required. A better understanding of the protective immune response in naturally infected patients is essential for vaccine design. Methods: We conducted a longitudina... Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1371/journal.pntd.0004152

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Institution:
University of Oxford
Department:
Oxford, MSD, NDM, Tropical Medicine, Thailand/Laos MOP
Role:
Author
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Funding agency for:
Dunachie, SJ
Wellcome Trust More from this funder
Publisher:
Public Library of Science Publisher's website
Journal:
PLoS Neglected Tropical Diseases Journal website
Volume:
9
Issue:
10
Pages:
Article: e0004152
Publication date:
2015-01-01
DOI:
ISSN:
1935-2735
URN:
uuid:dc8e395f-298a-416f-85cd-ea4051ee4401
Source identifiers:
573232
Local pid:
pubs:573232

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