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Genetic analysis of the epidermal differentiation complex (EDC) on human chromosome 1q21: chromosomal orientation, new markers, and a 6-Mb YAC contig.

Abstract:

The epidermal differentiation complex (EDC) unites a remarkable number of structurally, functionally, and evolutionarily related genes that play an important role in terminal differentiation of the human epidermis. It is localized within 2.05 Mb of region q21 on human chromosome 1. We have identified and characterized 24 yeast artificial chromosome (YAC) clones by mapping individual EDC genes, sequence-tagged site (STS) markers (D1S305, D1S442, D1S498, D1S1664), and 10 new region-specific pro...

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Publication status:
Published

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Publisher copy:
10.1006/geno.1996.0563

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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, WTC Human Genetics
Role:
Author
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Journal:
Genomics
Volume:
37
Issue:
3
Pages:
295-302
Publication date:
1996-11-05
DOI:
EISSN:
1089-8646
ISSN:
0888-7543
URN:
uuid:dc55920a-9edd-4fc8-b4da-3ac9a8af2dff
Source identifiers:
35994
Local pid:
pubs:35994

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