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Studies on the interaction of extended terpyridyl and triazine metal complexes with DNA.

Abstract:

The interaction with duplex DNA of a series of 12 previously synthesised ruthenium (II) complexes incorporating extended terpyridines or analogous ligands is reported. The interaction was investigated using absorption spectroscopy and also, when possible, luminescence spectroscopy. Binding parameters for the interactions were estimated using established models. It was found that binding affinities are relatively large and their magnitude is somewhat dependent on the metal centre attached to t...

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Publication status:
Published

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Institution:
University of Oxford
Department:
Oxford, MSD, Pathology Dunn School
Thomas, JA More by this author
Journal:
Journal of inorganic biochemistry
Volume:
100
Issue:
8
Pages:
1314-1319
Publication date:
2006-08-05
DOI:
EISSN:
1873-3344
ISSN:
0162-0134
URN:
uuid:dc52a7ae-671b-4bd5-9217-6983926f506e
Source identifiers:
240689
Local pid:
pubs:240689

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