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Association of Lipid Fractions With Risks for Coronary Artery Disease and Diabetes.

Abstract:

Importance: Low-density lipoprotein cholesterol (LDL-C) is causally related to coronary artery disease (CAD), but the relevance of high-density lipoprotein cholesterol (HDL-C) and triglycerides (TGs) is uncertain. Lowering of LDL-C levels by statin therapy modestly increases the risk of type 2 diabetes, but it is unknown whether this effect is specific to statins. Objective: To investigate the associations of 3 routinely measured lipid fractions with CAD and diabetes through mendelian randomi...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Accepted manuscript

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Publisher copy:
10.1001/jamacardio.2016.1884

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Department:
Oxford, MSD, Nuffield Department of Population Health, Clinical Trial Service Unit
Role:
Author
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Publisher:
American Medical Association Publisher's website
Journal:
JAMA Cardiology Journal website
Volume:
1
Issue:
6
Pages:
692-699
Publication date:
2016-08-03
Acceptance date:
2016-01-01
DOI:
EISSN:
2380-6591
ISSN:
2380-6583
Pubs id:
pubs:638205
URN:
uri:dc43da4c-9308-40f9-85bc-357374591402
UUID:
dc43da4c-9308-40f9-85bc-357374591402
Local pid:
pubs:638205
Paper number:
6

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