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Journal article

Optimization of bacterial whole cell bioreporters for toxicity assay of environmental samples.

Abstract:

In a study to optimize bacterial whole cell biosensors (bioreporters) for the detection of environmental contaminants, we constructed a toxicity sensing strain Acinetobacter baylyi ADP1_recA_lux. The ADP1_recA_lux is a chromosomally based bioreporter which makes the sensing system stable and negates the need for antibiotics to maintain the trait. The AOP1_recA_lux is activated to express bioluminescence when it is exposed to DNA damaging toxicants. Since the ADP1_recA_lux constantly expresses...

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Publication status:
Published

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Publisher copy:
10.1021/es901349r

Authors


Thornton, SF More by this author
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Institution:
University of Oxford
Department:
Oxford, MPLS, Engineering Science
Banwart, SA More by this author
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Journal:
Environmental science and technology
Volume:
43
Issue:
20
Pages:
7931-7938
Publication date:
2009-10-05
DOI:
EISSN:
1520-5851
ISSN:
0013-936X
URN:
uuid:dc231a57-9ccc-4dd4-9cac-4d7e216d62d7
Source identifiers:
63699
Local pid:
pubs:63699

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